Why do I need to Detox my body?

We are surrounded by chemicals that we ingest in various ways. From the air we breathe, to the water we drink, to where we play, 
our bodies rarely get a break from them. When the detoxification pathways are compromised hormonal imbalances occur, and in 
individuals with a history of drug exposure and chemical exposure this can cause an overload on the liver therefore decreasing its ability to get rid of toxins.

How do we get so toxic?
We are surrounded by environmental toxins in the air, water, in our food and food products. Our homes are full of chemicals as are our personal hygiene products.

Phthalates 
The phthalates out-gas from the plastics such as food containers, carpeting, vinyl shower curtains, and the tubing used in hospitals in IVs. They leach in to our food and beverages and are now found in our river lakes oceans, and water supplies. We eat so many plastics the government has established an average daily amount we digest. 

Our daily intake of plastic is so high that the government has evaluated it to be 210 mcg per day. Imagine that!!!!

How phthalates affect us
Phthalates disrupt the hormones in our body by sending wrong signals or blocking the receptor sites on our cells so the proper 
message cannot get through to the cell. They gum up our receptors so the hormones can’t work. Some of the outcomes are decreased energy and sex drive, hyperactivity and learning disabilities. Once they accumulate in our organs they can trigger cancers  of breast, lung, prostate, and thyroid.

Styrene from styrofoam cups is a carcinogen but the body lacks a mechanism to get rid of it, and EPA studies of human fat 
biopsies show styrene residues in 100% of people. A breast-feeding infant consumes 18X more carcinogen dioxin in one year through breast milk than the maximum “safe” lifetime dose. Childhood cancers are at an all time high and now rank #1 in the cause of death by disease in kids ages 1-15. Before getting pregnant it is wise to detox.

Air
Ohio is #1 in the country for toxic emissions. Dioxins, also found in foods, are created in part through the manufacturing of 
plastics, pesticides, and other chemicals. Smokestacks release it in the air, where it is absorbed by clouds. Rain releases them 
into the soil, where it is absorbed by the plants that we use for human and animal consumption.

Water 
USA Today recently reported that the average city water contains over 500 different chemicals. Poisoned by pesticide runoff, 
chemicals in the air, artificial fertilizers (made from toxic sewage sludge) and man- made chemicals such as chlorine and 
fluoride.

Chlorine 
Used to kill bugs and as a home cleanser, chlorine is a free radical initiator. It elevates cholesterol and accelerates aging. 
Articles have documented how chlorine in water increases atherosclerosis and various types of cancer of the rectum and bladder.

Fluoride
Fluoride is an enzyme inhibitor known to cause excessive calcification in arteries, joints, and ligaments. Fluoride may, in fact, contribute to cancer and osteoporosis. An eleven year study on 39,000 U.S. school kids done between 1986 and 1997 
showed no difference in tooth decay between kids drinking fluoridated and non-fluoridated water. Instead of building strong 
bones the study showed fluoride damaged brain enzymes and lowered IQs. Fluoride has also been linked to behavioral 
disorders, flu-like symptoms and arthritis. Fluoride also causes an increase in bone cancers and hip fractures by displacing 
minerals in the bone and replacing them with fluoride. 

Death rates are higher in fluoridated communities versus communities using well water. A U.S.NCI study showed a 70% 
increase in osteosarcoma (bone cancer) among young men in the fluoridated areas of Seattle and Iowa versus a 4% lower 
incidence in young men in non-fluoridated areas in the same states. Prozac contains flouride molecules

Excess Copper in Water
Copper from copper plumbing pipes can leech in to the acidic water. An alkaline water machine can reduce this problem.

Pesticides 
A catch all term for herbicides fungicides and insecticides, they are found in lawns and gardens, school yards, parks and golf 
courses as well as in all commercial grown crops that are not organic. We are also exposed to them through roadside spraying and aerial spraying for mosquitos, indoor pesticides. 

Monthly spraying for insect control is common practice in schools, commercial locations, restaurants and food preparation facilities and churches. In our homes, many of us use flea collars and flea shampoos on our pets. 

In lab animals, various cancers, immune deficiencies, intestinal and neurological diseases have been caused with as little as one dose of a pesticide. Pesticides interfere with neurotransmitters, cause infertility and genetic damage, and most have not been sufficiently tested.

Detergents
Contains a class of 100 chemical and their derivatives from petroleum based products. (Use Seventh Generation)
Alkyl phenol ethoxylates (APES) and Non-phenol ethoxylates (NPES) are found in cleaning products that remove grease or oil 
Nail lacquers, cosmetics, hair products soaps and shaving foams.

Researchers at Tufts University were surprised to find breast cancer cells growing in empty flasks. Further examination showed it was non-phenol ethoxylates (NPES), which has an estrogenic effect. NPES are contained in plastic bottles water bottles, baby food bottles and all plastic food containers. The funds for their research were suddenly no longer available. 

Xenohormones and Endocrine Disruptors
These hormones are like a virus on a computer, altering the sensitivity and number of receptors on the cell membrane, jamming signal or scrambling messages. Xenohormones disrupt the balance and interactions of the hormones and affect the neurotransmitters--our brain messengers. 

Cosmetics Shampoos and Lotions
Top ingredients of concern

Coal tar hair dye — Unlike other color additives, coal tar hair dyes are not screened by FDA for safety. They are widely used in 
popular brands despite studies linking them to bladder cancer and immune system damage. 

Alpha hydroxy acids (skin peelers) — Skin peeling products are designed to diminish wrinkles and blemishes, but in stripping off outer layers of skin, their use may also lead to increased skin cancer risk, and in some cases chemical burns and permanent scarring. 

Ingredients of Concern
Phthalates — These industrial plasticizers are widely added to nail polish and fragrance. Recent studies link them to impaired 
reproductive development in baby boys exposed in the womb or through breast milk. 

Fragrance — "Fragrance" mixtures, exempt from product labeling laws, can comprise hundreds of individual ingredients, and 
are common human allergens. A recent survey found that up to one of every 50 people suffer immune system damage from 
fragrance exposures. 
 
Want to find out how safe the products you use are? www.safe-cosmetics.org 

In the past 60 years over 87,000 man-made chemicals have been introduced into our food and water supply. Can you imagine the combined effect they may have on our body? What about prescription medications and their toxic effect on our liver and our body. Toxins stockpile in your body! Studies reveal that 100% of those studied showed dioxins, PCB’s, dichlorobenzene, and xylene. Dioxins and PCB’s are among the most potent causes of cancer. Babies in the mother’s womb are now showing over 200 toxins. 

How these toxins affects our bodies
They can interfere with the action of any hormone and hormones are the chemical messengers or our communication system of 
the body. These toxins can be related to cancers, PMS, Infertility, irregular menstrual bleeding, irregular cycles, thyroid problems, 
endometriosis, weight issues and more. 

Elimination Organs
The liver is the primary elimination organ, with the kidneys coming in second through urine. Constipation can hinder the 
elimination of toxins through the bowels. The skin contains 2 million sweat glands, or 18 Sq. feet 6 miles of skin ducts and the lungs remove gaseous poisons: CO2.

Detoxification and Purification Program 
The liver is the primary filter in our body, and is one of our body’s self defense mechanism. It has 300 billion unique cells and is 
responsible for neutralizing metabolic products, chemicals and toxins so they can be eliminated. The liver filters two and one half pints of blood per minute when body is at rest. In one year it filters enough blood to fill 23 milk trucks. The liver also has wonderful regenerative powers – if 90% of it is removed it may grow back to full size.

When the liver is impaired, toxins build up in the body. This can affect mood, behavior, and overall health, eventually building up 
free radicals that can harm many of our body systems. In addition to the breakdown and excretion of poisonous materials, the liver is responsible for over 500 separate activities.

In the liver there are two routes to breakdown toxins and chemical by products. 

Phase I Pathway turns compounds that are fat soluble in to water soluble compounds, preparing these products for Phase II pathway. 450 enzymes neutralize or breakdown metabolites into an intermediate compound that is then processed by the Phase II pathway. However, if the Phase I is too rapid, and Phase II cannot keep up, this results in a toxin overload. When this occurs, chronic illnesses can develop.

Phase II Pathway has to breakdown or bond with the intermediates from Phase I to make them easier to excrete through the kidneys via the urine. In Phase II the intermediate chemicals bind to certain amino acids and peptides, (Glutathione), carrying them into the gut so they can be excreted.

For every molecule of chemical that is detoxified, we use up, deplete or lose forever a molecule of glutathione, plus a molecule of ATP or energy. During Phase II there are six different pathways or routes to break these toxins down.

Phase II Pathways
Glutathione conjugation
Glycine (amino acid) conjugation
Methylation
Sulfation
Acetylation
Glucoronidation
1. Glutathione conjugation
In this process glutathione (which consists of glycine, cysteine and glutamic acid) binds with the Phase I substrates to become 
water soluble products so they can be excreted. The purpose of glutathione is to maintain the structure of the red blood cell 
membranes, and cellular proteins. It also helps carry sulphur containing AA in to the cells. 

Glutathione is available through diet and synthesis, but if you feed your body junk food, it doesn’t have the essential nutrients 
needed to make enough glutathione, leaving the body vulnerable to toxins and chemical exposures. 

What depletes the body of glutathione?
Smoking. It can also be depleted if the body is placed in oxidated stress such as infections, cancers, GI or pulmonary 
inflammation disorders. Taking B6, riboflavin, methionine, cysteine, glutamic acid, potassium, copper, zinc and selenium 
enhances glutathione production.

Methylation
This pathway involves the methyl groups of the Phase I endproducts. 
Requires beatine, pyradoxyl -5- phosphate, choline methionine, magnesium, methylcolbalamin, trimethylglycine, folic acid, 
vitamin C and vitamin E.

Sulfation
This pathway involves the sulfur containing groups of the Phase I endproducts. This pathway is for neurotransmitters, toxins, 
steroid and protein based hormones. Sulphur AA cystine, cysteine, taurine, and methionine.

Sulphur containing foods- eggs, cheese, meat poultry, nuts and legumes. Diets low in methionine and cysteine will decrease the sulfation pathway. A sign of faulty sulfoxidation is a strong urine odor after eating asparagus. 

Acetylation
This pathway binds toxins with acetyl Co-A and requires pantothenic acid, vitamin C and thiamin. 

Glucuronidation
Toxins will bind with glucuronic acid.

5% of the population may lack a specific enzyme (UDGPT) known as Gilbert’s Syndrome

Bile Excretion
Once the liver has detoxified these chemicals they are delivered to the bile for secretion into the intestines. If not enough bile is 
being made we must improve its function. 
GB problems such as difficulty digesting fats, flatulence, inability to tolerate fried foods, burping after meals.

Gall Bladder
If the gall bladder is removed the cystic duct acts as a reservoir for the bile. Synthesis and elimination of bile is necessary for optimal removal of toxins and hormones. Cholacol II is recommended if GB removed.

Detoxify your body by doing a well balanced detoxification and purification program. 


Detox/ Purification Program
Congratulations on taking an important step to regain your health!

The Detoxification Purification program

Detoxification Packet